Detailed information of TA system TA296834

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2046331..2046577
• Replicon: chromosome
• Accession: NZ_OX419565
• Organism: Bacillus subtilis isolate NRS6145

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: KJP64_RS10250
• Protein ID: WP_109789044.1
• Coordinates: 2046331..2046423 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2046404..2046577 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KJP64_RS10235 (NRS6145_10130)	2041490..2041825	+	336	WP_009967409.1	hypothetical protein	-
KJP64_RS10240 (NRS6145_10135)	2041872..2045477	-	3606	WP_213379451.1	P-loop NTPase fold protein	-
KJP64_RS10245	2045710..2046042	-	333	WP_026009814.1	hypothetical protein	-
KJP64_RS10250	2046331..2046423	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2046404..2046577	-	174	-	-	Antitoxin
KJP64_RS10255 (NRS6145_10145)	2046692..2047534	-	843	WP_003231327.1	hypothetical protein	-
KJP64_RS10260 (NRS6145_10150)	2047734..2048192	-	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
KJP64_RS10265 (NRS6145_10155)	2048202..2050004	-	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
KJP64_RS10270 (NRS6145_10160)	2050106..2050663	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2032316..2055994	23678

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T296834 WP_109789044.1 NZ_OX419565:2046331-2046423 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

Antitoxin

Nucleotide

• Length: 174 bp

>AT296834 NZ_OX419565:c2046577-2046404 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin