Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) bsrE-as-bsrE/-
Location 2046331..2046577 Replicon chromosome
Accession NZ_OX419565
Organism Bacillus subtilis isolate NRS6145

Toxin (Protein)


Gene name bsrE Uniprot ID -
Locus tag KJP64_RS10250 Protein ID WP_109789044.1
Coordinates 2046331..2046423 (+) Length 31 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2046404..2046577 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJP64_RS10235 (NRS6145_10130) 2041490..2041825 + 336 WP_009967409.1 hypothetical protein -
KJP64_RS10240 (NRS6145_10135) 2041872..2045477 - 3606 WP_213379451.1 P-loop NTPase fold protein -
KJP64_RS10245 2045710..2046042 - 333 WP_026009814.1 hypothetical protein -
KJP64_RS10250 2046331..2046423 + 93 WP_109789044.1 type I toxin-antitoxin system toxin BsrE Toxin
- 2046404..2046577 - 174 - - Antitoxin
KJP64_RS10255 (NRS6145_10145) 2046692..2047534 - 843 WP_003231327.1 hypothetical protein -
KJP64_RS10260 (NRS6145_10150) 2047734..2048192 - 459 WP_003231326.1 type VII secretion system immunity protein YobK -
KJP64_RS10265 (NRS6145_10155) 2048202..2050004 - 1803 WP_004399481.1 LXG family T7SS effector ribonuclease toxin YobL -
KJP64_RS10270 (NRS6145_10160) 2050106..2050663 - 558 WP_004399321.1 SMI1/KNR4 family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2032316..2055994 23678


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-24)


Sequences


Toxin        


Download         Length: 31 a.a.        Molecular weight: 3358.16 Da        Isoelectric Point: 4.1840

>T296834 WP_109789044.1 NZ_OX419565:2046331-2046423 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Download         Length: 93 bp


Antitoxin


Download         Length: 174 bp

>AT296834 NZ_OX419565:c2046577-2046404 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References