Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-SR6/-
Location 2255916..2256205 Replicon chromosome
Accession NZ_OX419564
Organism Bacillus subtilis isolate NRS6127

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag KJP48_RS11670 Protein ID WP_009967548.1
Coordinates 2255916..2256032 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2256027..2256205 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJP48_RS11640 (2251377) 2251377..2252615 - 1239 WP_142743355.1 MFS transporter -
KJP48_RS11645 (2252728) 2252728..2253978 - 1251 WP_114168635.1 UV damage repair protein UvrX -
KJP48_RS11650 (2253971) 2253971..2254303 - 333 WP_119996914.1 YolD-like family protein -
KJP48_RS11655 (2254477) 2254477..2254812 + 336 WP_213386198.1 hypothetical protein -
KJP48_RS11660 (2254855) 2254855..2255211 - 357 WP_213386197.1 hypothetical protein -
KJP48_RS11665 (2255217) 2255217..2255684 - 468 WP_213386196.1 DUF4879 domain-containing protein -
KJP48_RS11670 (2255916) 2255916..2256032 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- (2256027) 2256027..2256205 - 179 NuclAT_1 - Antitoxin
- (2256027) 2256027..2256205 - 179 NuclAT_1 - Antitoxin
- (2256027) 2256027..2256205 - 179 NuclAT_1 - Antitoxin
- (2256027) 2256027..2256205 - 179 NuclAT_1 - Antitoxin
KJP48_RS11675 (2256310) 2256310..2256843 - 534 WP_163260209.1 GNAT family protein -
KJP48_RS11680 (2256879) 2256879..2257457 - 579 WP_069322724.1 SMI1/KNR4 family protein -
KJP48_RS11685 (2257513) 2257513..2257974 - 462 WP_042976288.1 SMI1/KNR4 family protein -
KJP48_RS11690 (2257990) 2257990..2259755 - 1766 Protein_2251 T7SS effector LXG polymorphic toxin -
KJP48_RS11695 (2260007) 2260007..2261008 + 1002 WP_250628844.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2132614..2265676 133062


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T296828 WP_009967548.1 NZ_OX419564:2255916-2256032 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

Antitoxin


Download         Length: 179 bp

>AT296828 NZ_OX419564:c2256205-2256027 [Bacillus subtilis]
AATGATACAAATAATTATTTTTTGCATTTTGATTTGTAGAAATGCATAAAATAAAAAGACCAGGGTGCTACCAACACCCC
AGCTCTGTACAAAAAGCTGCCCATCAAAGGGCTTGCTCAGATGTATGTGACATAGTAGACCAACCCTTTAGGGTCGCAAT
CTCAAGGGGAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References