Detailed information of TA system TA296822

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2205151..2205368
• Replicon: chromosome
• Accession: NZ_OX419564
• Organism: Bacillus subtilis isolate NRS6127

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: A0A6H0WKE8
• Locus tag: KJP48_RS11415
• Protein ID: WP_032721653.1
• Coordinates: 2205192..2205368 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2205151..2205251 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KJP48_RS11370	2200705..2201259	-	555	WP_213386207.1	hypothetical protein	-
KJP48_RS11375	2201568..2201933	-	366	WP_213386206.1	hypothetical protein	-
KJP48_RS11380	2201967..2202236	-	270	WP_006640590.1	hypothetical protein	-
KJP48_RS11385	2202268..2202471	-	204	WP_213386204.1	hypothetical protein	-
KJP48_RS11390	2202535..2202738	-	204	WP_213386203.1	hypothetical protein	-
KJP48_RS11395	2202831..2203076	-	246	WP_144500927.1	hypothetical protein	-
KJP48_RS11400	2203390..2204607	-	1218	WP_144500928.1	hypothetical protein	-
KJP48_RS11405	2204689..2204877	-	189	WP_003230987.1	hypothetical protein	-
KJP48_RS11410	2204922..2205173	-	252	WP_134853524.1	hypothetical protein	-
-	2205151..2205251	+	101	-	-	Antitoxin
KJP48_RS11415	2205192..2205368	-	177	WP_032721653.1	hypothetical protein	Toxin
-	2205309..2205409	+	101	NuclAT_0	-	-
-	2205309..2205409	+	101	NuclAT_0	-	-
-	2205309..2205409	+	101	NuclAT_0	-	-
-	2205309..2205409	+	101	NuclAT_0	-	-
KJP48_RS11420	2206317..2206511	+	195	WP_072692657.1	hypothetical protein	-
KJP48_RS11425	2206551..2209058	+	2508	WP_213393208.1	hypothetical protein	-
KJP48_RS11430	2209322..2209597	+	276	WP_144500930.1	HU family DNA-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2132614..2265676	133062

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6850.39 Da
• Isoelectric Point: 12.8833

>T296822 WP_032721653.1 NZ_OX419564:c2205368-2205192 [Bacillus subtilis]
VLEKVGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

Antitoxin

Nucleotide

• Length: 101 bp

>AT296822 NZ_OX419564:2205151-2205251 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Toxin

• AlphaFold DB: A0A6H0WKE8

Antitoxin