Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrG/-
Location 1853160..1853449 Replicon chromosome
Accession NZ_OX419553
Organism Bacillus subtilis isolate NRS6183

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag KJP78_RS09350 Protein ID WP_009967548.1
Coordinates 1853333..1853449 (-) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 1853160..1853338 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJP78_RS09325 (1848751) 1848751..1849004 + 254 Protein_1780 hypothetical protein -
KJP78_RS09330 (1849070) 1849070..1849627 + 558 WP_153912309.1 SMI1/KNR4 family protein -
KJP78_RS09335 (1849727) 1849727..1851637 + 1911 WP_041056183.1 ribonuclease YeeF family protein -
KJP78_RS09340 (1851644) 1851644..1852132 + 489 WP_041056186.1 antitoxin YezG family protein -
KJP78_RS09345 (1852146) 1852146..1852709 + 564 WP_250533594.1 SMI1/KNR4 family protein -
- (1853160) 1853160..1853338 + 179 NuclAT_1 - Antitoxin
- (1853160) 1853160..1853338 + 179 NuclAT_1 - Antitoxin
- (1853160) 1853160..1853338 + 179 NuclAT_1 - Antitoxin
- (1853160) 1853160..1853338 + 179 NuclAT_1 - Antitoxin
KJP78_RS09350 (1853333) 1853333..1853449 - 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
KJP78_RS09355 (1853682) 1853682..1854149 + 468 WP_128992107.1 DUF4879 domain-containing protein -
KJP78_RS09360 (1854155) 1854155..1854511 + 357 WP_019712874.1 hypothetical protein -
KJP78_RS09365 (1854554) 1854554..1854889 - 336 WP_004399073.1 hypothetical protein -
KJP78_RS09370 (1855063) 1855063..1855395 + 333 WP_128473977.1 YolD-like family protein -
KJP78_RS09375 (1855388) 1855388..1856638 + 1251 WP_213416709.1 UV damage repair protein UvrX -
KJP78_RS09380 (1856751) 1856751..1857989 + 1239 WP_142743355.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1838965..2012799 173834


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T296764 WP_009967548.1 NZ_OX419553:c1853449-1853333 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

Antitoxin


Download         Length: 179 bp

>AT296764 NZ_OX419553:1853160-1853338 [Bacillus subtilis]
AATGATACAAATAATTATTTTTTGCATTTTGATTTGTAGAAATGCATAAAATAAAAAGACCAGGGTGCTACCAACACCCC
AGCTCTGTACAAAAAGCTGCCCATCAAAGGGCTTGCTCAGATGTATGTGACATAGTAGACCAACCCTTTAGGGTCGCAAT
CTCAAGGGGAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References