296747

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 2005968..2006601 Replicon chromosome
Accession NZ_OX411212
Organism Vibrio campbellii isolate BF5_0283

Toxin (Protein)


Gene name higB Uniprot ID A0A347UQS4
Locus tag QMX76_RS09895 Protein ID WP_012600340.1
Coordinates 2006269..2006601 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QMX76_RS09890 Protein ID WP_017049537.1
Coordinates 2005968..2006282 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMX76_RS09850 2001616..2002047 - 432 WP_005536215.1 hypothetical protein -
QMX76_RS09855 2002184..2002639 - 456 WP_282249272.1 GNAT family N-acetyltransferase -
QMX76_RS09860 2002756..2003256 - 501 WP_282249273.1 GNAT family N-acetyltransferase -
QMX76_RS09865 2003402..2003899 - 498 WP_282249274.1 GNAT family N-acetyltransferase -
QMX76_RS09870 2003927..2004016 - 90 WP_073514058.1 DUF3265 domain-containing protein -
QMX76_RS09875 2004548..2004637 - 90 WP_080286084.1 DUF3265 domain-containing protein -
QMX76_RS09880 2005283..2005840 - 558 WP_282249275.1 nucleotidyltransferase family protein -
QMX76_RS09885 2005861..2005953 - 93 WP_080102040.1 DUF3265 domain-containing protein -
QMX76_RS09890 2005968..2006282 - 315 WP_017049537.1 DNA-binding transcriptional regulator Antitoxin
QMX76_RS09895 2006269..2006601 - 333 WP_012600340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QMX76_RS09900 2006704..2006796 - 93 WP_079855829.1 DUF3265 domain-containing protein -
QMX76_RS09905 2006811..2007323 - 513 WP_231571918.1 GNAT family N-acetyltransferase -
QMX76_RS09910 2007457..2008014 - 558 WP_282249276.1 cysteine hydrolase -
QMX76_RS09915 2008044..2008133 - 90 WP_079852034.1 DUF3265 domain-containing protein -
QMX76_RS09920 2008151..2008528 - 378 WP_282249277.1 hypothetical protein -
QMX76_RS09925 2008564..2008653 - 90 WP_072609597.1 DUF3265 domain-containing protein -
QMX76_RS09930 2008684..2009037 - 354 WP_282249278.1 DUF6404 family protein -
QMX76_RS09935 2009089..2009180 - 92 Protein_1884 DUF3265 domain-containing protein -
QMX76_RS09940 2009233..2009994 - 762 WP_282249279.1 nucleotidyltransferase domain-containing protein -
QMX76_RS09945 2010112..2011137 - 1026 WP_282249280.1 LD-carboxypeptidase -
QMX76_RS09950 2011163..2011255 - 93 WP_282249281.1 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1980022..2048688 68666
- inside Integron - - 1992543..2039497 46954


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(4-104)

Antitoxin

Antitoxin MqsA/HigA-2

(24-101)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12906.76 Da        Isoelectric Point: 10.0960

>T296747 WP_012600340.1 NZ_OX411212:c2006601-2006269 [Vibrio campbellii]
MKSVFVESTIFEKYRNEYLSDDEFRLFQAELMSNPKQGDVIQGTGGLRKIRVASKGKGKRGGSRVIYYFLDEKRRFYLLT
IYGKNEMSDLTADQKKQLKAFMEAWRNEQS

Download         Length: 333 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11704.17 Da        Isoelectric Point: 6.3290

>AT296747 WP_017049537.1 NZ_OX411212:c2006282-2005968 [Vibrio campbellii]
MSNRDLFAELSSALVEAKEHSEGKLTLKTHQVNDISELNISPDEIVSIREQFNMSRGVFARLLHTSSRTLENWEQGRSAP
NGQAVTLLKLVQRHPETLSHIAEL

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A347UQS4

Antitoxin

Source ID Structure

References