Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4740631..4741331 Replicon chromosome
Accession NZ_OX352324
Organism Pseudomonas sp. MM221

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag OM991_RS22240 Protein ID WP_264360167.1
Coordinates 4741035..4741331 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag OM991_RS22235 Protein ID WP_264360166.1
Coordinates 4740631..4741032 (-) Length 134 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM991_RS22215 (GLGCALEP_04615) 4735768..4736589 - 822 WP_264360163.1 transporter substrate-binding domain-containing protein -
OM991_RS22220 (GLGCALEP_04616) 4736665..4737594 - 930 WP_264360164.1 FAD-binding protein -
OM991_RS22225 (GLGCALEP_04617) 4737595..4738344 - 750 WP_016498683.1 electron transfer flavoprotein subunit beta/FixA family protein -
OM991_RS22230 (GLGCALEP_04618) 4738895..4740559 + 1665 WP_264360165.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
OM991_RS22235 (GLGCALEP_04619) 4740631..4741032 - 402 WP_264360166.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
OM991_RS22240 (GLGCALEP_04620) 4741035..4741331 - 297 WP_264360167.1 type II toxin-antitoxin system MqsR family toxin Toxin
OM991_RS22245 (GLGCALEP_04621) 4741425..4742750 - 1326 WP_264360168.1 MFS transporter -
OM991_RS22250 (GLGCALEP_04622) 4742823..4743302 - 480 WP_264360169.1 histidine kinase -
OM991_RS22255 (GLGCALEP_04623) 4743471..4743947 - 477 WP_264360170.1 sigma-70 family RNA polymerase sigma factor -
OM991_RS22260 (GLGCALEP_04624) 4744167..4745339 + 1173 WP_264360171.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-96)

Antitoxin

(3-46)


Sequences


Toxin        


Download         Length: 99 a.a.        Molecular weight: 11054.99 Da        Isoelectric Point: 9.4795

>T296639 WP_264360167.1 NZ_OX352324:c4741331-4741035 [Pseudomonas sp. MM221]
MEKRTPHCPLERVRALAAARCIRPTGAALRGAKALGMDYPGMLEVISSLERTDFYKSMTSHMDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKGL

Download         Length: 297 bp


Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14541.62 Da        Isoelectric Point: 4.9438

>AT296639 WP_264360166.1 NZ_OX352324:c4741032-4740631 [Pseudomonas sp. MM221]
MKCPICGGAELAPDVQGMPFSYKGEATVIPDVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNATVVDPSFIASMRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References