296632

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 5683263..5684053 Replicon chromosome
Accession NZ_OX352322
Organism Pseudomonas sp. MM223

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag ONI07_RS26420 Protein ID WP_264360720.1
Coordinates 5683586..5684053 (+) Length 156 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID I7C311
Locus tag ONI07_RS26415 Protein ID WP_014859917.1
Coordinates 5683263..5683589 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONI07_RS26395 (DBADOPDK_05389) 5678862..5679923 - 1062 WP_264360716.1 HlyD family secretion protein -
ONI07_RS26400 (DBADOPDK_05390) 5679952..5681493 - 1542 WP_264360717.1 MFS transporter -
ONI07_RS26405 5681608..5682515 - 908 Protein_5189 LysR family transcriptional regulator -
ONI07_RS26410 (DBADOPDK_05393) 5682725..5683171 + 447 WP_264360718.1 universal stress protein -
ONI07_RS26415 (DBADOPDK_05394) 5683263..5683589 + 327 WP_014859917.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
ONI07_RS26420 (DBADOPDK_05395) 5683586..5684053 + 468 WP_264360720.1 type II toxin-antitoxin system YhaV family toxin Toxin
ONI07_RS26425 (DBADOPDK_05396) 5684103..5684963 - 861 WP_264360721.1 HlyD family secretion protein -
ONI07_RS26430 (DBADOPDK_05397) 5684974..5685174 - 201 WP_008097766.1 DUF1656 domain-containing protein -
ONI07_RS26435 (DBADOPDK_05398) 5685164..5687341 - 2178 WP_264387208.1 FUSC family protein -
ONI07_RS26440 (DBADOPDK_05399) 5687338..5688867 - 1530 WP_264360722.1 efflux transporter outer membrane subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(17-152)

Antitoxin

PrlF antitoxin

(8-106)


Sequences

Toxin        


Download         Length: 156 a.a.        Molecular weight: 17954.42 Da        Isoelectric Point: 9.9065

>T296632 WP_264360720.1 NZ_OX352322:5683586-5684053 [Pseudomonas sp. MM223]
MSDASRKPLVIHGWTVIAHPLFLAKLDALSAQVQAQMHKDPTGYTSRNAYKRLAAIKRLAFDVIPQDPTKPEYRQGATLG
GDHKHWFRAKFFQQYRLFFRYHTPSRIIVLAWVNDESSKRAYESSDDAYKVFQKMLHTGHPPDDWEQLLREAAAE

Download         Length: 468 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 11919.40 Da        Isoelectric Point: 4.3722

>AT296632 WP_014859917.1 NZ_OX352322:5683263-5683589 [Pseudomonas sp. MM223]
MAATFDVESTLTDRYQTTVPETVRRALGLKKRDKIHYSIRPDGGVILTRAEATEDDPVLGKFLDFLAHDIATNPQRLQVV
DAGLIARLDKLVGDAEVDLDQPLSADDE

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I7C311

References