Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2763353..2763616 Replicon chromosome
Accession NZ_OX344719
Organism Staphylococcus aureus strain ST20190863 isolate ST20190863

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OOL12_RS13915 Protein ID WP_001802298.1
Coordinates 2763353..2763457 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2763452..2763616 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOL12_RS13885 2758737..2759519 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
OOL12_RS13890 2759587..2760444 + 858 WP_000370924.1 HAD family hydrolase -
OOL12_RS13895 2760676..2760860 - 185 Protein_2701 exotoxin -
OOL12_RS13900 2761149..2761241 - 93 WP_001790138.1 hypothetical protein -
OOL12_RS13905 2761530..2762666 + 1137 WP_264717378.1 SAP domain-containing protein -
OOL12_RS13910 2762709..2763192 + 484 Protein_2704 recombinase family protein -
OOL12_RS13915 2763353..2763457 + 105 WP_001802298.1 hypothetical protein Toxin
- 2763452..2763616 - 165 - - Antitoxin
OOL12_RS13925 2763957..2765048 - 1092 WP_000495671.1 lytic regulatory protein -
OOL12_RS13930 2765314..2766294 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
OOL12_RS13935 2766296..2766616 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OOL12_RS13940 2766768..2767433 + 666 WP_001024094.1 SDR family oxidoreductase -
OOL12_RS13945 2767868..2768569 + 702 WP_264717379.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T296608 WP_001802298.1 NZ_OX344719:2763353-2763457 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT296608 NZ_OX344719:c2763616-2763452 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References