Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 180459..180641 Replicon chromosome
Accession NZ_OX344719
Organism Staphylococcus aureus strain ST20190863 isolate ST20190863

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag OOL12_RS01090 Protein ID WP_001801861.1
Coordinates 180546..180641 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 180459..180518 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOL12_RS01075 179597..179974 + 378 WP_001037045.1 DUF1433 domain-containing protein -
OOL12_RS01080 180168..180344 + 177 Protein_176 transposase -
OOL12_RS01085 180322..180423 - 102 WP_001791893.1 hypothetical protein -
- 180459..180518 + 60 - - Antitoxin
OOL12_RS01090 180546..180641 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
OOL12_RS01095 180844..180987 + 144 WP_001549059.1 transposase -
OOL12_RS01100 181591..181974 + 384 WP_000070811.1 hypothetical protein -
OOL12_RS01105 181985..182161 + 177 WP_000375476.1 hypothetical protein -
OOL12_RS01110 182163..182348 + 186 WP_000809857.1 hypothetical protein -
OOL12_RS01115 182462..183103 + 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
OOL12_RS01120 183321..183872 - 552 WP_000414205.1 hypothetical protein -
OOL12_RS01125 183970..184314 - 345 WP_000627551.1 DUF3969 family protein -
OOL12_RS01130 184355..184981 - 627 WP_000669046.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T296601 WP_001801861.1 NZ_OX344719:c180641-180546 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

Antitoxin


Download         Length: 60 bp

>AT296601 NZ_OX344719:180459-180518 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References