Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 710930..711507 Replicon chromosome
Accession NZ_OX336137
Organism Nitrospina watsonii strain 347 isolate Nitrospina watsonii

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QML71_RS03185 Protein ID WP_282010455.1
Coordinates 710930..711214 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QML71_RS03190 Protein ID WP_282010456.1
Coordinates 711214..711507 (+) Length 98 a.a.

Genomic Context


QML71_RS03165QML71_RS03170QML71_RS03175QML71_RS03180QML71_RS03185QML71_RS03190QML71_RS03195QML71_RS03200QML71_RS03205QML71_RS03160
Location: 708466..709122 (657 bp)
Type: Others
Protein ID: WP_282010451.1
Location: 709131..709427 (297 bp)
Type: Others
Protein ID: WP_282010452.1
Location: 709867..710436 (570 bp)
Type: Others
Protein ID: WP_282010453.1
Location: 710610..710837 (228 bp)
Type: Others
Protein ID: WP_282010454.1
Location: 710930..711214 (285 bp)
Type: Toxin
Protein ID: WP_282010455.1
Location: 711214..711507 (294 bp)
Type: Antitoxin
Protein ID: WP_282010456.1
Location: 711542..711796 (255 bp)
Type: Others
Protein ID: WP_282010457.1
Location: 711816..714581 (2766 bp)
Type: Others
Protein ID: WP_282010458.1
Location: 714578..716047 (1470 bp)
Type: Others
Protein ID: WP_282010459.1
Location: 707235..707708 (474 bp)
Type: Others
Protein ID: WP_282010450.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QML71_RS03160 (NSPWAT_0654)707235..707708-474WP_282010450.1hypothetical protein-
QML71_RS03165 (NSPWAT_0655)708466..709122+657WP_282010451.1AAA family ATPase-
QML71_RS03170 (NSPWAT_0656)709131..709427+297WP_282010452.1hypothetical protein-
QML71_RS03175 (NSPWAT_0657)709867..710436+570WP_282010453.1hypothetical protein-
QML71_RS03180 (NSPWAT_0658)710610..710837+228WP_282010454.1hypothetical protein-
QML71_RS03185 (NSPWAT_0659)710930..711214+285WP_282010455.1type II toxin-antitoxin system RelE/ParE family toxinToxin
QML71_RS03190 (NSPWAT_0660)711214..711507+294WP_282010456.1HigA family addiction module antitoxinAntitoxin
QML71_RS03195 (NSPWAT_0661)711542..711796+255WP_282010457.1HigA family addiction module antitoxin-
QML71_RS03200 (NSPWAT_0662)711816..714581+2766WP_282010458.1type I restriction-modification enzyme R subunit C-terminal domain-containing protein-
QML71_RS03205 (NSPWAT_0663)714578..716047+1470WP_282010459.1restriction endonuclease subunit S-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-94)

Antitoxin

(5-88)


Sequences


Toxin        


Download         Length: 95 a.a.        Molecular weight: 10904.59 Da        Isoelectric Point: 10.3389

>T296581 WP_282010455.1 NZ_OX336137:710930-711214 [Nitrospina watsonii]
MKIKKVRHRGLKRFIEKNDPSGLPSAKVEKVRDIITALVVAESPNDLPVFPGWRLHRLKGDRKGQWSISVTGNWRITFVL
EDDTIQELNLEDYH

Download         Length: 285 bp


Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11124.98 Da        Isoelectric Point: 9.9205

>AT296581 WP_282010456.1 NZ_OX336137:711214-711507 [Nitrospina watsonii]
MKNIGMIPSHPGEFVRRQVLEPLELSISHAAEILDIRRATLSDLVNGKTSLTPEMAFRLEKAFDVKMDFLLRMQALYDTA
RMRQSGKNIDVVRFHPN

Download         Length: 294 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References