Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2645769..2645953 Replicon chromosome
Accession NC_021670
Organism Staphylococcus aureus Bmb9393

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag SABB_RS13720 Protein ID WP_000482650.1
Coordinates 2645846..2645953 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2645769..2645829 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SABB_RS13695 2641299..2641466 - 168 WP_001790576.1 hypothetical protein -
SABB_RS13705 2641697..2643430 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
SABB_RS13710 2643455..2645218 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2645769..2645829 + 61 - - Antitoxin
SABB_RS13720 2645846..2645953 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
SABB_RS13725 2646087..2646473 - 387 WP_000779358.1 flippase GtxA -
SABB_RS13730 2646741..2647883 + 1143 WP_001176863.1 glycerate kinase -
SABB_RS13735 2647943..2648602 + 660 WP_000831298.1 membrane protein -
SABB_RS13740 2648784..2649995 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
SABB_RS13745 2650118..2650591 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T29637 WP_000482650.1 NC_021670:c2645953-2645846 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T29637 NC_021670:c2645953-2645846 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT29637 NC_021670:2645769-2645829 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References