Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2352404..2352683 Replicon chromosome
Accession NC_021670
Organism Staphylococcus aureus Bmb9393

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SABB_RS12140 Protein ID WP_001802298.1
Coordinates 2352579..2352683 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2352404..2352583 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SABB_RS12120 2348603..2349268 - 666 WP_001024094.1 SDR family oxidoreductase -
SABB_RS12125 2349420..2349740 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SABB_RS12130 2349742..2350722 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
SABB_RS12135 2350988..2352079 + 1092 WP_000495671.1 lytic regulatory protein -
- 2352404..2352583 + 180 - - Antitoxin
SABB_RS12140 2352579..2352683 - 105 WP_001802298.1 hypothetical protein Toxin
SABB_RS16540 2352844..2353327 - 484 Protein_2319 recombinase family protein -
SABB_RS12150 2353370..2354506 - 1137 WP_000115564.1 SAP domain-containing protein -
SABB_RS12155 2354795..2354887 + 93 WP_001790138.1 hypothetical protein -
SABB_RS12160 2355592..2356449 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
SABB_RS12165 2356517..2357299 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T29632 WP_001802298.1 NC_021670:c2352683-2352579 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T29632 NC_021670:c2352683-2352579 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT29632 NC_021670:2352404-2352583 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References