Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 4117121..4117766 Replicon chromosome
Accession NZ_OW970315
Organism Pantoea agglomerans strain DAPP-PG734

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OOS96_RS19315 Protein ID WP_022625232.1
Coordinates 4117413..4117766 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OOS96_RS19310 Protein ID WP_022625233.1
Coordinates 4117121..4117420 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOS96_RS19295 (DAPPPG734_19590) 4113034..4114818 - 1785 WP_010252112.1 GMC family oxidoreductase -
OOS96_RS19300 (DAPPPG734_19595) 4114821..4115555 - 735 WP_264704756.1 gluconate 2-dehydrogenase subunit 3 family protein -
OOS96_RS19305 (DAPPPG734_19600) 4115832..4117073 + 1242 WP_010672044.1 peptide antibiotic transporter SbmA -
OOS96_RS19310 (DAPPPG734_19605) 4117121..4117420 - 300 WP_022625233.1 helix-turn-helix transcriptional regulator Antitoxin
OOS96_RS19315 (DAPPPG734_19610) 4117413..4117766 - 354 WP_022625232.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OOS96_RS19320 (DAPPPG734_19615) 4117976..4119028 - 1053 WP_031591752.1 YncE family protein -
OOS96_RS19325 (DAPPPG734_19620) 4119231..4119440 - 210 WP_009092571.1 DUF1471 domain-containing protein -
OOS96_RS19330 (DAPPPG734_19625) 4119653..4120840 - 1188 WP_010252123.1 MFS transporter -
OOS96_RS19335 (DAPPPG734_19630) 4120945..4121910 + 966 WP_031591753.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-107)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-88)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13407.28 Da        Isoelectric Point: 6.4741

>T296234 WP_022625232.1 NZ_OW970315:c4117766-4117413 [Pantoea agglomerans]
MWDVDTTKRFDEWFKAQSEELKEDMLAAIVILSEYGPHLARPFADTVDGSDFPNMKELRVQHQGKPIRAFFAFDPSRRGI
VLCAGDKTGVKEKKFYKDMIKLADAEFRKYLNGGDNG

Download         Length: 354 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11131.98 Da        Isoelectric Point: 9.8103

>AT296234 WP_022625233.1 NZ_OW970315:c4117420-4117121 [Pantoea agglomerans]
MANLKELMANQSPESRERIAKKVDAMRQVIALHMLREELNLSQTEMAHAMGVKQPTIARMEQADNDPRLSTLKRYVTALG
GEISIDVKLPTGKRIAFDL

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References