Detailed information of TA system TA029623

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2014274..2014456
• Replicon: chromosome
• Accession: NC_021670
• Organism: Staphylococcus aureus Bmb9393

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SABB_RS16420
• Protein ID: WP_001801861.1
• Coordinates: 2014274..2014369 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2014397..2014456 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SABB_RS10050	2009934..2010560	+	627	WP_000669046.1	hypothetical protein	-
SABB_RS10055	2010601..2010945	+	345	WP_000627551.1	DUF3969 family protein	-
SABB_RS10060	2011043..2011594	+	552	WP_041205412.1	hypothetical protein	-
SABB_RS10065	2011812..2012453	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
SABB_RS10070	2012567..2012752	-	186	WP_000809857.1	hypothetical protein	-
SABB_RS10075	2012754..2012930	-	177	WP_000375476.1	hypothetical protein	-
SABB_RS10080	2012941..2013324	-	384	WP_000070811.1	hypothetical protein	-
SABB_RS10090	2013928..2014071	-	144	WP_001549059.1	transposase	-
SABB_RS16420	2014274..2014369	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	2014397..2014456	-	60	-	-	Antitoxin
SABB_RS10095	2014492..2014593	+	102	WP_001791893.1	hypothetical protein	-
SABB_RS15890	2014571..2014747	-	177	Protein_1964	transposase	-
SABB_RS10100	2014941..2015318	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	1987508..2046294	58786

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T29623 WP_001801861.1 NC_021670:2014274-2014369 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T29623 NC_021670:2014274-2014369 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT29623 NC_021670:c2014456-2014397 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin