Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2543467..2543651 Replicon chromosome
Accession NC_021554
Organism Staphylococcus aureus CA-347

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag CA347_RS13010 Protein ID WP_000482647.1
Coordinates 2543544..2543651 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2543467..2543527 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CA347_RS12990 2539053..2539220 - 168 WP_031785511.1 hypothetical protein -
CA347_RS13000 2539451..2541184 - 1734 WP_000488492.1 ABC transporter ATP-binding protein/permease -
CA347_RS13005 2541233..2542972 - 1740 WP_001064831.1 ABC transporter ATP-binding protein/permease -
CA347_RS15620 2543350..2543517 - 168 WP_000301894.1 hypothetical protein -
- 2543467..2543527 + 61 - - Antitoxin
CA347_RS13010 2543544..2543651 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
CA347_RS13015 2543785..2544171 - 387 WP_000779354.1 flippase GtxA -
CA347_RS13020 2544439..2545581 + 1143 WP_001176860.1 glycerate kinase -
CA347_RS13025 2545641..2546300 + 660 WP_000831298.1 membrane protein -
CA347_RS13030 2546480..2547691 + 1212 WP_001191975.1 multidrug effflux MFS transporter -
CA347_RS13035 2547814..2548287 - 474 WP_000456491.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T29577 WP_000482647.1 NC_021554:c2543651-2543544 [Staphylococcus aureus CA-347]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T29577 NC_021554:c2543651-2543544 [Staphylococcus aureus CA-347]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT29577 NC_021554:2543467-2543527 [Staphylococcus aureus CA-347]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References