Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1076620..1077132 Replicon chromosome
Accession NZ_OW724079
Organism Streptococcus sp. Marseille-Q3533

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NBW44_RS05375 Protein ID WP_250307520.1
Coordinates 1076620..1076874 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NBW44_RS05380 Protein ID WP_250307521.1
Coordinates 1076878..1077132 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBW44_RS05360 1073696..1074010 - 315 WP_006153745.1 DNA-directed RNA polymerase subunit omega -
NBW44_RS05365 1074035..1074661 - 627 WP_250307518.1 guanylate kinase -
NBW44_RS05370 1074798..1076411 - 1614 WP_250307519.1 ribonuclease Y -
NBW44_RS05375 1076620..1076874 - 255 WP_250307520.1 Txe/YoeB family addiction module toxin Toxin
NBW44_RS05380 1076878..1077132 - 255 WP_250307521.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NBW44_RS05385 1077266..1078363 - 1098 WP_250307522.1 nucleotidyltransferase -
NBW44_RS05390 1078373..1079113 - 741 WP_284346465.1 class I SAM-dependent methyltransferase -
NBW44_RS05395 1079473..1079826 - 354 WP_250307523.1 ribosome silencing factor -
NBW44_RS05400 1079827..1080420 - 594 WP_250307524.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
NBW44_RS05405 1080420..1081049 - 630 WP_036759262.1 nicotinate-nucleotide adenylyltransferase -
NBW44_RS05410 1081100..1081411 - 312 WP_250307525.1 ribosome assembly RNA-binding protein YhbY -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10115.55 Da        Isoelectric Point: 7.9716

>T295514 WP_250307520.1 NZ_OW724079:c1076874-1076620 [Streptococcus sp. Marseille-Q3533]
MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGKPEPLKYDYQGAWSRRIDAENRIIYMMDGDSVAFLSF
KDHY

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9753.04 Da        Isoelectric Point: 5.6227

>AT295514 WP_250307521.1 NZ_OW724079:c1077132-1076878 [Streptococcus sp. Marseille-Q3533]
MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKSEWNSIQETLRIAQNKELSDKVLRGISQVRAGHTQVH
VIEE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References