Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4891392..4892092 Replicon chromosome
Accession NC_021491
Organism Pseudomonas putida H8234

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag L483_RS22890 Protein ID WP_024717923.1
Coordinates 4891796..4892092 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A8I0Z3K6
Locus tag L483_RS22885 Protein ID WP_024717924.1
Coordinates 4891392..4891793 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L483_RS22865 4886529..4887350 - 822 WP_016488288.1 transporter substrate-binding domain-containing protein -
L483_RS22870 4887426..4888355 - 930 WP_016488289.1 FAD-binding protein -
L483_RS22875 4888356..4889105 - 750 WP_016488290.1 electron transfer flavoprotein subunit beta/FixA family protein -
L483_RS22880 4889639..4891321 + 1683 WP_080641073.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
L483_RS22885 4891392..4891793 - 402 WP_024717924.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
L483_RS22890 4891796..4892092 - 297 WP_024717923.1 type II toxin-antitoxin system MqsR family toxin Toxin
L483_RS22895 4892187..4893512 - 1326 WP_016488294.1 MFS transporter -
L483_RS22900 4893585..4894064 - 480 WP_016488295.1 hypothetical protein -
L483_RS22905 4894364..4894825 + 462 WP_016488296.1 azurin -
L483_RS22910 4894863..4895363 - 501 WP_016488297.1 sigma-70 family RNA polymerase sigma factor -
L483_RS22915 4895594..4896775 + 1182 WP_024717922.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11161.07 Da        Isoelectric Point: 9.0375

>T29529 WP_024717923.1 NC_021491:c4892092-4891796 [Pseudomonas putida H8234]
MEKRTPHCPLERVKVLAAARRISPTGAALRGARALGMDYPGMLEVISCLERSDFYKSMTSHMDHRVWQDVYRPLTAFGYV
YLKVSVVDDVLIVSFKEL

Download         Length: 297 bp

>T29529 NC_021491:c4892092-4891796 [Pseudomonas putida H8234]
ATGGAAAAGAGAACGCCTCACTGTCCGTTGGAAAGGGTAAAAGTCTTGGCTGCTGCCAGGCGCATCAGCCCTACAGGCGC
TGCACTGAGAGGCGCCAGAGCCCTGGGAATGGATTATCCGGGCATGCTTGAAGTGATCTCCTGTTTGGAGCGTAGTGATT
TCTACAAGAGCATGACCAGCCATATGGATCACCGCGTTTGGCAGGACGTCTATCGTCCGCTTACAGCATTTGGGTACGTT
TATCTGAAAGTGTCCGTGGTAGACGACGTGCTCATCGTGTCTTTCAAGGAGTTGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14516.57 Da        Isoelectric Point: 4.7550

>AT29529 WP_024717924.1 NC_021491:c4891793-4891392 [Pseudomonas putida H8234]
MRCPVCGGAELAPDVQGMPYSYKGEATVIPDVSGDYCCACGECVLSHDEAMRVSNLMTAFERQVNAAVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT29529 NC_021491:c4891793-4891392 [Pseudomonas putida H8234]
ATGAGATGTCCAGTATGCGGCGGTGCGGAGCTTGCACCTGATGTTCAGGGGATGCCCTATAGCTATAAAGGAGAGGCGAC
CGTCATCCCTGACGTAAGTGGCGATTACTGTTGCGCCTGTGGTGAATGTGTACTTAGCCACGATGAAGCCATGCGTGTCA
GTAACCTGATGACGGCATTCGAGCGTCAAGTCAACGCAGCTGTTGTGGATCCTTCCTTCATTGCTTCAATCCGCCGTAAG
TTCGACCTCGACCAGCGTGAAGCGGGGGAAATTTTCGGGGGTGGCGTCAACGCGTTCTCCCGTTATGAAAACGGCAAGAC
CACACCACCCGTGGCGTTGGTGAAACTGCTCAAGCTGCTGGATCGCCATCCAGAACTCTTCGAGGAAGTGCGTACTGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References