Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 125150..125658 Replicon chromosome
Accession NZ_OV996158
Organism Enterococcus mundtii strain P2005

Toxin (Protein)


Gene name yoeB Uniprot ID A0A2K8TBN6
Locus tag N7O26_RS00620 Protein ID WP_071866576.1
Coordinates 125389..125658 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag N7O26_RS00615 Protein ID WP_260697295.1
Coordinates 125150..125404 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7O26_RS00600 121050..121685 + 636 WP_217809051.1 ABC transporter ATP-binding protein -
N7O26_RS00605 121703..122125 + 423 WP_065096980.1 hypothetical protein -
N7O26_RS00610 123178..124797 + 1620 WP_260697294.1 alpha-glucosidase -
N7O26_RS00615 125150..125404 + 255 WP_260697295.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N7O26_RS00620 125389..125658 + 270 WP_071866576.1 Txe/YoeB family addiction module toxin Toxin
N7O26_RS00625 125880..126314 + 435 WP_010736432.1 MarR family transcriptional regulator -
N7O26_RS00630 126411..127517 + 1107 WP_071866577.1 NADH-dependent flavin oxidoreductase -
N7O26_RS00635 127534..128211 + 678 WP_019722542.1 type 1 glutamine amidotransferase domain-containing protein -
N7O26_RS00640 128238..129098 + 861 WP_071866606.1 aldo/keto reductase -
N7O26_RS00645 129365..129889 - 525 WP_081367415.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-58)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10592.47 Da        Isoelectric Point: 10.3790

>T295070 WP_071866576.1 NZ_OV996158:125389-125658 [Enterococcus mundtii]
MGYLIEIKKNAKKDFTKLKSAGLHKKFDELLKVIRKNPFQSPPPYEKLVGIPYYSRRINIQHRLVYSVDIEREIVTILSV
WSHYERGLF

Download         Length: 270 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9613.72 Da        Isoelectric Point: 4.0768

>AT295070 WP_260697295.1 NZ_OV996158:125150-125404 [Enterococcus mundtii]
MEVITPTKARNNLYSLIKHVVAGNQPVEIINTKSEDESVVIISKADWNAIQETLYLQNTGVLNQIKHYEEEETEELGEID
WDTL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K8TBN6

Antitoxin

Source ID Structure

References