Detailed information of TA system TA295025

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2383427..2383611
• Replicon: chromosome
• Accession: NZ_OV648025
• Organism: Staphylococcus argenteus isolate 20S00001-1_long

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: MD993_RS11415
• Protein ID: WP_000482653.1
• Coordinates: 2383504..2383611 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2383427..2383487 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MD993_RS11405	2379279..2381012	-	1734	WP_031787186.1	ABC transporter ATP-binding protein	-
MD993_RS11410	2381037..2382800	-	1764	WP_031787187.1	ABC transporter ATP-binding protein	-
-	2383427..2383487	+	61	-	-	Antitoxin
MD993_RS11415	2383504..2383611	-	108	WP_000482653.1	type I toxin-antitoxin system Fst family toxin	Toxin
MD993_RS11420	2383745..2384131	-	387	WP_000779346.1	flippase GtxA	-
MD993_RS11425	2384399..2385541	+	1143	WP_031787188.1	glycerate kinase	-
MD993_RS11430	2385600..2386259	+	660	WP_000831306.1	membrane protein	-
MD993_RS11435	2386444..2387655	+	1212	WP_031787189.1	multidrug effflux MFS transporter	-
MD993_RS11440	2387771..2388250	-	480	WP_031787190.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	sbi / hlgA / hlgA / hlgC / hlgB	2368066..2384131	16065

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4025.81 Da
• Isoelectric Point: 11.0582

>T295025 WP_000482653.1 NZ_OV648025:c2383611-2383504 [Staphylococcus argenteus]
MFNLLINIMTTAISGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 61 bp

>AT295025 NZ_OV648025:2383427-2383487 [Staphylococcus argenteus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin