Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | HipBST/HipA(toxin) |
Location | 1231854..1233087 | Replicon | chromosome |
Accession | NZ_OU957226 | ||
Organism | Flavobacterium sp. CECT 9288 isolate UB20; 130122 CR 30 |
Toxin (Protein)
Gene name | HipT | Uniprot ID | - |
Locus tag | LQ189_RS05325 | Protein ID | WP_230154786.1 |
Coordinates | 1232197..1233087 (+) | Length | 297 a.a. |
Antitoxin (Protein)
Gene name | HipS | Uniprot ID | - |
Locus tag | LQ189_RS05320 | Protein ID | WP_230154784.1 |
Coordinates | 1231854..1232168 (+) | Length | 105 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LQ189_RS05305 (FVB9288_01104) | 1230259..1230900 | - | 642 | WP_230154778.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
LQ189_RS05310 (FVB9288_01105) | 1230900..1231397 | - | 498 | WP_230154780.1 | helix-turn-helix domain-containing protein | - |
LQ189_RS05315 (FVB9288_01107) | 1231642..1231851 | + | 210 | WP_230154782.1 | helix-turn-helix transcriptional regulator | - |
LQ189_RS05320 (FVB9288_01108) | 1231854..1232168 | + | 315 | WP_230154784.1 | HipA N-terminal domain-containing protein | Antitoxin |
LQ189_RS05325 (FVB9288_01109) | 1232197..1233087 | + | 891 | WP_230154786.1 | HipA domain-containing protein | Toxin |
LQ189_RS05330 (FVB9288_01110) | 1233100..1233498 | - | 399 | WP_230158635.1 | NUDIX domain-containing protein | - |
LQ189_RS05335 (FVB9288_01111) | 1233709..1236069 | - | 2361 | WP_230154788.1 | DUF2357 domain-containing protein | - |
LQ189_RS05340 (FVB9288_01112) | 1236076..1237941 | - | 1866 | WP_230154791.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 297 a.a. Molecular weight: 34178.78 Da Isoelectric Point: 9.1875
>T294950 WP_230154786.1 NZ_OU957226:1232197-1233087 [Flavobacterium sp. CECT 9288]
MDKYSEKGLRMIAPKLTYLNDLPYTAVELRQEAANRAKKLSIQGVQPKLSAAISIVDQEFKIVDQFGTYIIKPQNDLFPQ
LPENEDVTMRMAKVFGLEVPFHGMLYGKDGSLSYFIKRFDRYGKGSKYATEDFAQLTGNTRDTKYRYTMEKLVPVMDEYC
SFPAIEKANFFKRILFCYLTGNEDMHLKNFSVITKNGKTTLAPIYDFLNSTIAIKNPEEEIALTLKGKKSNLKAADFVCY
YAQERLQLNEKTIATILLQMKKATPKWKELLEISFLSDEMKEKYLELLEIRVGMFK
MDKYSEKGLRMIAPKLTYLNDLPYTAVELRQEAANRAKKLSIQGVQPKLSAAISIVDQEFKIVDQFGTYIIKPQNDLFPQ
LPENEDVTMRMAKVFGLEVPFHGMLYGKDGSLSYFIKRFDRYGKGSKYATEDFAQLTGNTRDTKYRYTMEKLVPVMDEYC
SFPAIEKANFFKRILFCYLTGNEDMHLKNFSVITKNGKTTLAPIYDFLNSTIAIKNPEEEIALTLKGKKSNLKAADFVCY
YAQERLQLNEKTIATILLQMKKATPKWKELLEISFLSDEMKEKYLELLEIRVGMFK
Download Length: 891 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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