Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 1231854..1233087 Replicon chromosome
Accession NZ_OU957226
Organism Flavobacterium sp. CECT 9288 isolate UB20; 130122 CR 30

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag LQ189_RS05325 Protein ID WP_230154786.1
Coordinates 1232197..1233087 (+) Length 297 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag LQ189_RS05320 Protein ID WP_230154784.1
Coordinates 1231854..1232168 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ189_RS05305 (FVB9288_01104) 1230259..1230900 - 642 WP_230154778.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
LQ189_RS05310 (FVB9288_01105) 1230900..1231397 - 498 WP_230154780.1 helix-turn-helix domain-containing protein -
LQ189_RS05315 (FVB9288_01107) 1231642..1231851 + 210 WP_230154782.1 helix-turn-helix transcriptional regulator -
LQ189_RS05320 (FVB9288_01108) 1231854..1232168 + 315 WP_230154784.1 HipA N-terminal domain-containing protein Antitoxin
LQ189_RS05325 (FVB9288_01109) 1232197..1233087 + 891 WP_230154786.1 HipA domain-containing protein Toxin
LQ189_RS05330 (FVB9288_01110) 1233100..1233498 - 399 WP_230158635.1 NUDIX domain-containing protein -
LQ189_RS05335 (FVB9288_01111) 1233709..1236069 - 2361 WP_230154788.1 DUF2357 domain-containing protein -
LQ189_RS05340 (FVB9288_01112) 1236076..1237941 - 1866 WP_230154791.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(40-265)

Antitoxin

HipA, N-terminal subdomain 1

(4-98)


Sequences

Toxin        


Download         Length: 297 a.a.        Molecular weight: 34178.78 Da        Isoelectric Point: 9.1875

>T294950 WP_230154786.1 NZ_OU957226:1232197-1233087 [Flavobacterium sp. CECT 9288]
MDKYSEKGLRMIAPKLTYLNDLPYTAVELRQEAANRAKKLSIQGVQPKLSAAISIVDQEFKIVDQFGTYIIKPQNDLFPQ
LPENEDVTMRMAKVFGLEVPFHGMLYGKDGSLSYFIKRFDRYGKGSKYATEDFAQLTGNTRDTKYRYTMEKLVPVMDEYC
SFPAIEKANFFKRILFCYLTGNEDMHLKNFSVITKNGKTTLAPIYDFLNSTIAIKNPEEEIALTLKGKKSNLKAADFVCY
YAQERLQLNEKTIATILLQMKKATPKWKELLEISFLSDEMKEKYLELLEIRVGMFK

Download         Length: 891 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11784.48 Da        Isoelectric Point: 4.8668

>AT294950 WP_230154784.1 NZ_OU957226:1231854-1232168 [Flavobacterium sp. CECT 9288]
MRRAIVFAHGKRAGVLTEIAANDYHFEYDENYDGEAVSLTMPTTQKKYSYTFFPPFFEGLLPEGVMLEGLLRIVKIDKKD
YFSQLIATGNDLVGAVTVKLKEDE

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References