Detailed information of TA system TA294581

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 66483..66697
• Replicon: plasmid contig000002
• Accession: NZ_OD940438
• Organism: Enterococcus faecalis isolate BX8117

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: KJA90_RS14345
• Protein ID: WP_002360667.1
• Coordinates: 66483..66593 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	66633..66697 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KJA90_RS14305	61668..61874	+	207	Protein_67	transposase	-
KJA90_RS14310	62404..63024	+	621	WP_021732893.1	recombinase family protein	-
KJA90_RS14315	63041..63328	+	288	WP_010708491.1	hypothetical protein	-
KJA90_RS14320	63322..63546	+	225	WP_010708492.1	ultraviolet resistance protein UvrA repressor UvrC	-
KJA90_RS14325	63607..63816	+	210	WP_002387638.1	hypothetical protein	-
KJA90_RS14760	63978..64130	+	153	WP_225850000.1	DUF6440 family protein	-
KJA90_RS14335	64557..65885	+	1329	WP_021732894.1	ultraviolet resistance protein UvrA	-
KJA90_RS14340	65882..66232	+	351	WP_002399364.1	hypothetical protein	-
KJA90_RS14765	66189..66401	+	213	WP_002360669.1	hypothetical protein	-
KJA90_RS14345	66483..66593	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	66633..66697	-	65	-	-	Antitoxin
KJA90_RS14350	66833..67129	+	297	WP_002360665.1	replication control protein PrgN	-
KJA90_RS14355	67383..68165	+	783	WP_002360664.1	ParA family protein	-
KJA90_RS14360	68158..68514	+	357	WP_002360663.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Mobilizable plasmid	-	prgB/asc10	1..68773	68773

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T294581 WP_002360667.1 NZ_OD940438:66483-66593 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

Antitoxin

Nucleotide

• Length: 65 bp

>AT294581 NZ_OD940438:c66697-66633 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin