Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2697149..2697488 Replicon chromosome
Accession NZ_OD940434
Organism Enterococcus faecalis isolate BX5936

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag KJA96_RS12980 Protein ID WP_078130893.1
Coordinates 2697149..2697298 (+) Length 50 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2697272..2697488 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJA96_RS12965 2692805..2693437 - 633 WP_002358972.1 RloB family protein -
KJA96_RS12970 2693446..2694741 - 1296 WP_010820355.1 ATP-binding protein -
KJA96_RS12975 2695203..2696819 + 1617 WP_078130894.1 phosphatase PAP2/LCP family protein -
KJA96_RS12980 2697149..2697298 + 150 WP_078130893.1 type I toxin-antitoxin system toxin PepG1 Toxin
- 2697272..2697488 - 217 - - Antitoxin
KJA96_RS14215 2697489..2702176 - 4688 Protein_2543 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(16-49)


Sequences

Toxin        


Download         Length: 50 a.a.        Molecular weight: 5766.10 Da        Isoelectric Point: 11.3858

>T294565 WP_078130893.1 NZ_OD940434:2697149-2697298 [Enterococcus faecalis]
MRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIVLIVKLLKNDKKK

Download         Length: 150 bp

Antitoxin


Download         Length: 217 bp

>AT294565 NZ_OD940434:c2697488-2697272 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATA
ATGGTAATGAAAAGAGAGGTATGCGACAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTGACCTTTTTAGTTACAA
AAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References