Detailed information of TA system TA294527

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 1172301..1172636
• Replicon: chromosome
• Accession: NZ_OD940422
• Organism: Enterococcus faecalis isolate WE0851

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: KJA80_RS05480
• Protein ID: WP_002415596.1
• Coordinates: 1172301..1172444 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	1172586..1172636 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KJA80_RS05460	1167418..1167633	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
KJA80_RS05465	1167772..1168764	+	993	WP_002358973.1	biotin--[acetyl-CoA-carboxylase] ligase	-
KJA80_RS05470	1169028..1169666	-	639	WP_002375448.1	lytic polysaccharide monooxygenase	-
KJA80_RS05475	1170353..1171969	+	1617	WP_002415597.1	phosphatase PAP2/LCP family protein	-
KJA80_RS05480	1172301..1172444	+	144	WP_002415596.1	type I toxin-antitoxin system toxin PepG1	Toxin
-	1172586..1172636	+	51	-	-	Antitoxin
KJA80_RS05485	1172637..1176404	-	3768	WP_010712914.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5314.46 Da
• Isoelectric Point: 10.6323

>T294527 WP_002415596.1 NZ_OD940422:1172301-1172444 [Enterococcus faecalis]
MNVSAKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 51 bp

>AT294527 NZ_OD940422:1172586-1172636 [Enterococcus faecalis]
AATAAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Structures

Antitoxin