Detailed information of TA system TA294523

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-RNAII/-
• Location: 1100179..1100578
• Replicon: chromosome
• Accession: NZ_OD940422
• Organism: Enterococcus faecalis isolate WE0851

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: KJA80_RS05150
• Protein ID: WP_002367458.1
• Coordinates: 1100179..1100322 (-)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	1100434..1100578 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KJA80_RS05135	1095471..1096184	-	714	WP_002415630.1	trehalose operon repressor	-
KJA80_RS14000	1096287..1096421	-	135	WP_002415629.1	hypothetical protein	-
KJA80_RS05140	1096445..1099189	+	2745	WP_002415628.1	glycosyl hydrolase family 65 protein	-
KJA80_RS05145	1099204..1099854	+	651	WP_002415627.1	beta-phosphoglucomutase	-
KJA80_RS05150	1100179..1100322	-	144	WP_002367458.1	type I toxin-antitoxin system toxin PepG1	Toxin
-	1100434..1100578	+	145	-	-	Antitoxin
KJA80_RS14005	1100666..1100791	-	126	WP_002383214.1	hypothetical protein	-
KJA80_RS05155	1101075..1101608	+	534	WP_002415626.1	CPBP family intramembrane metalloprotease	-
KJA80_RS05160	1101662..1102633	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
KJA80_RS05165	1102808..1103245	-	438	WP_002354871.1	peptide-methionine (R)-S-oxide reductase MsrB	-
KJA80_RS05170	1103378..1103932	-	555	WP_002354869.1	Maf family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5311.50 Da
• Isoelectric Point: 10.8331

>T294523 WP_002367458.1 NZ_OD940422:c1100322-1100179 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 145 bp

>AT294523 NZ_OD940422:1100434-1100578 [Enterococcus faecalis]
TTGTGCTATAATAAAAACGAAAAGAGAGATATGCGTCAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCGAT
TTTGTTACAAAAAATAACCGTACTCAGTCAAAGTAAACGGTTATTTTTTATTGTCATTTTTAACA

Structures

Antitoxin