Detailed information of TA system TA294516

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 1026855..1027078
• Replicon: chromosome
• Accession: NZ_OD940422
• Organism: Enterococcus faecalis isolate WE0851

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: KJA80_RS04820
• Protein ID: WP_228759711.1
• Coordinates: 1026977..1027078 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	1026855..1027040 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KJA80_RS04795	1022472..1023425	-	954	WP_002415458.1	siderophore ABC transporter substrate-binding protein	-
KJA80_RS04800	1023464..1024219	-	756	WP_002415456.1	ATP-binding cassette domain-containing protein	-
KJA80_RS04805	1024216..1025181	-	966	WP_002415455.1	iron chelate uptake ABC transporter family permease subunit	-
KJA80_RS04810	1025178..1026125	-	948	WP_002375573.1	iron chelate uptake ABC transporter family permease subunit	-
KJA80_RS04815	1026310..1026762	+	453	WP_002367417.1	YueI family protein	-
-	1026855..1027040	+	186	-	-	Antitoxin
KJA80_RS04820	1026977..1027078	-	102	WP_228759711.1	putative holin-like toxin	Toxin
KJA80_RS04825	1027269..1029539	-	2271	WP_002354955.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
KJA80_RS04830	1029710..1030210	+	501	WP_002415453.1	cysteine hydrolase family protein	-
KJA80_RS04835	1031009..1031905	+	897	WP_002368434.1	YitT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3683.42 Da
• Isoelectric Point: 4.2645

>T294516 WP_228759711.1 NZ_OD940422:c1027078-1026977 [Enterococcus faecalis]
MSIEATLELMISFATLVALLIFDILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 186 bp

>AT294516 NZ_OD940422:1026855-1027040 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCCTTTATACCAACGCCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTT
TTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATATCGA
AAATCAGTAACGCAACAAGGGTTGCA

Structures

Antitoxin