Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2873147..2873481 Replicon chromosome
Accession NZ_OD940420
Organism Enterococcus faecalis isolate WE0438

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag KJA91_RS13750 Protein ID WP_002415596.1
Coordinates 2873147..2873290 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2873223..2873481 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJA91_RS13730 (2868264) 2868264..2868479 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
KJA91_RS13735 (2868618) 2868618..2869610 + 993 WP_002358973.1 biotin--[acetyl-CoA-carboxylase] ligase -
KJA91_RS13740 (2869874) 2869874..2870512 - 639 WP_002375448.1 lytic polysaccharide monooxygenase -
KJA91_RS13745 (2871199) 2871199..2872815 + 1617 WP_002415597.1 phosphatase PAP2/LCP family protein -
KJA91_RS13750 (2873147) 2873147..2873290 + 144 WP_002415596.1 type I toxin-antitoxin system toxin PepG1 Toxin
- (2873223) 2873223..2873481 - 259 NuclAT_2 - Antitoxin
- (2873432) 2873432..2873482 + 51 NuclAT_13 - -
KJA91_RS13755 (2873483) 2873483..2877250 - 3768 WP_010712914.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5314.46 Da        Isoelectric Point: 10.6323

>T294511 WP_002415596.1 NZ_OD940420:2873147-2873290 [Enterococcus faecalis]
MNVSAKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 144 bp

Antitoxin


Download         Length: 259 bp

>AT294511 NZ_OD940420:c2873481-2873223 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTTATTGATGGTCTTTTTAGGGTTGTTGTGCTATAA
TGATAAAGAAAAGAGAGATATGCTTCCAACATATCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCAATTTTATTATTT
AAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAA
GCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References