Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 489956..490182 Replicon chromosome
Accession NZ_OD940420
Organism Enterococcus faecalis isolate WE0438

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag KJA91_RS14530 Protein ID WP_219843903.1
Coordinates 489956..490066 (+) Length 37 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 489977..490182 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJA91_RS02420 (485388) 485388..487646 + 2259 WP_010716808.1 DNA helicase PcrA -
KJA91_RS02425 (487772) 487772..489802 + 2031 WP_002398122.1 NAD-dependent DNA ligase LigA -
KJA91_RS14530 (489956) 489956..490066 + 111 WP_219843903.1 putative holin-like toxin Toxin
- (489977) 489977..490182 - 206 NuclAT_6 - Antitoxin
KJA91_RS02430 (490384) 490384..490689 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
KJA91_RS02435 (490689) 490689..492158 + 1470 WP_002398120.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
KJA91_RS02440 (492158) 492158..493588 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
KJA91_RS02445 (493607) 493607..494695 + 1089 WP_002355572.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-33)


Sequences

Toxin        


Download         Length: 37 a.a.        Molecular weight: 3805.59 Da        Isoelectric Point: 5.9482

>T294495 WP_219843903.1 NZ_OD940420:489956-490066 [Enterococcus faecalis]
MSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 111 bp

Antitoxin


Download         Length: 206 bp

>AT294495 NZ_OD940420:c490182-489977 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAGTAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References