Detailed information of TA system TA294485

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 662020..662278
• Replicon: chromosome
• Accession: NZ_NQJO01000001
• Organism: Erwinia amylovora strain CTBT3-1 tig00000000

Toxin (Protein)

• Gene name: hok
• Uniprot ID: -
• Locus tag: CS942_RS19385
• Protein ID: WP_306475332.1
• Coordinates: 662162..662278 (+)
• Length: 39 a.a.

Antitoxin (RNA)

Gene name	sok
Locus tag	-
Coordinates	662020..662066 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CS942_RS18975	657466..657609	-	144	WP_004160049.1	hypothetical protein	-
CS942_RS03115	658082..658474	-	393	WP_004160048.1	DoxX family protein	-
CS942_RS03120	658684..658965	-	282	WP_004160039.1	YqjK-like family protein	-
CS942_RS03125	658965..659357	-	393	WP_004160038.1	phage holin family protein	-
CS942_RS03130	659359..659664	-	306	WP_004160037.1	DUF883 family protein	-
CS942_RS03135	659707..660078	-	372	WP_004160036.1	DUF1090 domain-containing protein	-
CS942_RS03140	660246..660638	-	393	WP_004160035.1	EnvZ/OmpR regulon moderator MzrA	-
CS942_RS03145	660635..661309	-	675	WP_004160034.1	DedA family protein	-
-	662020..662066	-	47	-	-	Antitoxin
CS942_RS19385	662162..662278	+	117	WP_306475332.1	type I toxin-antitoxin system Hok family toxin	Toxin
CS942_RS03165	662422..663654	-	1233	WP_099257836.1	serine/threonine transporter SstT	-
CS942_RS03170	663889..664869	-	981	WP_013035818.1	TerC family protein	-
CS942_RS03175	665282..666973	+	1692	WP_004160025.1	chloride channel protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (1-34)

Sequences

Toxin

Protein

• Length: 39 a.a.
• Molecular weight: 4439.23 Da
• Isoelectric Point: 8.4861

>T294485 WP_306475332.1 NZ_NQJO01000001:662162-662278 [Erwinia amylovora]
VCVTLLIFTYLTRKSLCEIRYKDGYREVAAFMAYESGK

Nucleotide

• Length: 117 bp

>T294485 NZ_NQJO01000001:662162-662278 [Erwinia amylovora]
GTGTGTGTCACGCTTTTAATATTCACATATCTGACACGAAAATCGCTCTGCGAAATTCGCTATAAGGATGGTTACAGGGA
GGTGGCCGCTTTCATGGCTTACGAATCCGGCAAGTAG

Antitoxin

Nucleotide

• Length: 47 bp

>AT294485 NZ_NQJO01000001:c662066-662020 [Erwinia amylovora]
GCATGCAGATGGCCTCGTGGATTAATGAAAATTAACTACGGGGCTTT

Structures

Antitoxin