294471

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1995187..1995465 Replicon chromosome
Accession NZ_LT996891
Organism Staphylococcus aureus isolate 24117-WT

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DYY95_RS10120 Protein ID WP_001802298.1
Coordinates 1995187..1995291 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1995287..1995465 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DYY95_RS10095 1991983..1992765 + 783 WP_000908174.1 ABC transporter ATP-binding protein -
DYY95_RS10100 1992833..1993690 + 858 WP_000370931.1 Cof-type HAD-IIB family hydrolase -
DYY95_RS10110 1994349..1994507 - 159 WP_001792784.1 hypothetical protein -
DYY95_RS10120 1995187..1995291 + 105 WP_001802298.1 hypothetical protein Toxin
- 1995287..1995465 - 179 - - Antitoxin
DYY95_RS10125 1996099..1997745 + 1647 WP_000277718.1 IS1182 family transposase -
DYY95_RS10130 1997774..1998865 - 1092 WP_000495672.1 hypothetical protein -
DYY95_RS10135 1999131..2000111 - 981 WP_000019739.1 CDF family zinc efflux transporter CzrB -
DYY95_RS10140 2000113..2000433 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1996099..1997745 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T294471 WP_001802298.1 NZ_LT996891:1995187-1995291 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 179 bp

>AT294471 NZ_LT996891:c1995465-1995287 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References