294468

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1715236..1715420 Replicon chromosome
Accession NZ_LT996891
Organism Staphylococcus aureus isolate 24117-WT

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DYY95_RS08585 Protein ID WP_000482647.1
Coordinates 1715236..1715343 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1715360..1715420 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DYY95_RS08560 1710608..1711081 + 474 WP_000456492.1 GyrI-like domain-containing protein -
DYY95_RS08565 1711204..1712415 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
DYY95_RS08570 1712597..1713256 - 660 WP_000831295.1 hypothetical protein -
DYY95_RS08575 1713316..1714458 - 1143 WP_001176863.1 glycerate kinase -
DYY95_RS08580 1714716..1715102 + 387 WP_000779360.1 flippase GtxA -
DYY95_RS08585 1715236..1715343 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1715360..1715420 - 61 - - Antitoxin
DYY95_RS08595 1716047..1717810 + 1764 WP_001064836.1 ABC transporter ATP-binding protein/permease -
DYY95_RS08600 1717835..1719568 + 1734 WP_000486496.1 ABC transporter ATP-binding protein/permease -
DYY95_RS08610 1719799..1719966 + 168 WP_001792506.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T294468 WP_000482647.1 NZ_LT996891:1715236-1715343 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT294468 NZ_LT996891:c1715420-1715360 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References