Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 640413..641074 Replicon chromosome
Accession NZ_LT996886
Organism Tessaracoccus timonensis strain Marseille-P5995

Toxin (Protein)


Gene name HigB2 Uniprot ID -
Locus tag DHT94_RS03120 Protein ID WP_108872309.1
Coordinates 640724..641074 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name HigA2 Uniprot ID -
Locus tag DHT94_RS03115 Protein ID WP_108872308.1
Coordinates 640413..640718 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DHT94_RS03095 636197..636592 - 396 WP_108870557.1 VOC family protein -
DHT94_RS03100 637190..637405 + 216 WP_108870558.1 ribbon-helix-helix protein, CopG family -
DHT94_RS03105 637468..637686 + 219 WP_108872307.1 type II toxin-antitoxin system RelE/ParE family toxin -
DHT94_RS03110 638087..640165 + 2079 WP_159087338.1 ATP-dependent endonuclease -
DHT94_RS03115 640413..640718 - 306 WP_108872308.1 helix-turn-helix domain-containing protein Antitoxin
DHT94_RS03120 640724..641074 - 351 WP_108872309.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DHT94_RS03125 641242..644226 - 2985 WP_108870560.1 DEAD/DEAH box helicase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-84)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13272.10 Da        Isoelectric Point: 6.4802

>T294434 WP_108872309.1 NZ_LT996886:c641074-640724 [Tessaracoccus timonensis]
MWSVDIELIAGWLASLDNDSREQVVAAIELLEDRGPQLGRPIVDTVSSSRHRNMKELRPGSSGRTELRILFAFDPVREAI
MLIAGDKSGSWKRWYARNIPRADDLFDEHLRRLKGE

Download         Length: 351 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11334.94 Da        Isoelectric Point: 8.5560

>AT294434 WP_108872308.1 NZ_LT996886:c640718-640413 [Tessaracoccus timonensis]
MAISLKDFVANHPVDRERVDAHKERMLAEVRAYRLRELREQAGLTQAQLAERIGVGQRQISKIEHGDVENAKVGTIRRYL
EAVGGGLAIEYVLGDQRVQVA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References