294335

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2015217..2015401 Replicon chromosome
Accession NZ_LT992477
Organism Staphylococcus aureus isolate 22_LA_562

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DXE38_RS10065 Protein ID WP_000482647.1
Coordinates 2015217..2015324 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2015341..2015401 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE38_RS10040 2010574..2011047 + 474 WP_000456489.1 GyrI-like domain-containing protein -
DXE38_RS10045 2011170..2012381 - 1212 WP_001191974.1 multidrug effflux MFS transporter -
DXE38_RS10050 2012569..2013228 - 660 WP_000831300.1 hypothetical protein -
DXE38_RS10055 2013288..2014430 - 1143 WP_001176859.1 glycerate kinase -
DXE38_RS10060 2014697..2015083 + 387 WP_000779355.1 flippase GtxA -
DXE38_RS10065 2015217..2015324 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2015341..2015401 - 61 - - Antitoxin
DXE38_RS10075 2016028..2017791 + 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
DXE38_RS10080 2017816..2019549 + 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
DXE38_RS10090 2019780..2019947 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T294335 WP_000482647.1 NZ_LT992477:2015217-2015324 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT294335 NZ_LT992477:c2015401-2015341 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References