Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 873232..873511 Replicon chromosome
Accession NZ_LT992476
Organism Staphylococcus aureus isolate 21_LA_436

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DXE57_RS04490 Protein ID WP_001802298.1
Coordinates 873232..873336 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 873332..873511 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE57_RS04455 869131..869739 + 609 WP_000101714.1 TIR domain-containing protein -
DXE57_RS04460 870029..870811 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
DXE57_RS04465 870879..871736 + 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
DXE57_RS04470 871866..871958 - 93 WP_000220902.1 hypothetical protein -
DXE57_RS04475 872394..872552 - 159 WP_001792784.1 hypothetical protein -
DXE57_RS04490 873232..873336 + 105 WP_001802298.1 hypothetical protein Toxin
- 873332..873511 - 180 - - Antitoxin
DXE57_RS04495 873834..874925 - 1092 WP_000495673.1 hypothetical protein -
DXE57_RS04500 875191..876171 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
DXE57_RS04505 876173..876493 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DXE57_RS04510 876645..877310 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T294318 WP_001802298.1 NZ_LT992476:873232-873336 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 180 bp

>AT294318 NZ_LT992476:c873511-873332 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References