Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 534229..534413 Replicon chromosome
Accession NZ_LT992476
Organism Staphylococcus aureus isolate 21_LA_436

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DXE57_RS02540 Protein ID WP_000482647.1
Coordinates 534229..534336 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 534353..534413 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE57_RS02515 529586..530059 + 474 WP_000456489.1 GyrI-like domain-containing protein -
DXE57_RS02520 530182..531393 - 1212 WP_001191974.1 multidrug effflux MFS transporter -
DXE57_RS02525 531581..532240 - 660 WP_000831300.1 hypothetical protein -
DXE57_RS02530 532300..533442 - 1143 WP_001176859.1 glycerate kinase -
DXE57_RS02535 533709..534095 + 387 WP_000779355.1 flippase GtxA -
DXE57_RS02540 534229..534336 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 534353..534413 - 61 - - Antitoxin
DXE57_RS02550 535040..536803 + 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
DXE57_RS02555 536828..538561 + 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
DXE57_RS02565 538792..538959 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T294313 WP_000482647.1 NZ_LT992476:534229-534336 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT294313 NZ_LT992476:c534413-534353 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References