Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1361676..1361873 Replicon chromosome
Accession NZ_LT992475
Organism Staphylococcus aureus isolate 20_LA_415

Toxin (Protein)


Gene name SprG2 Uniprot ID -
Locus tag DXE41_RS07195 Protein ID WP_000623369.1
Coordinates 1361766..1361873 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1361676..1361713 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE41_RS07160 1356777..1357133 + 357 WP_000766009.1 DoxX family protein -
DXE41_RS07165 1357222..1357410 - 189 WP_157958947.1 poly(glycerol-phosphate) alpha-glucosyltransferase -
DXE41_RS07170 1357500..1357790 + 291 WP_001796515.1 hypothetical protein -
DXE41_RS07175 1357878..1358519 - 642 WP_000571192.1 ABC transporter ATP-binding protein -
DXE41_RS07180 1358516..1358836 - 321 WP_000668623.1 YxeA family protein -
DXE41_RS07185 1358839..1360803 - 1965 WP_000870811.1 bacteriocin-associated integral membrane family protein -
DXE41_RS07190 1360847..1361131 - 285 WP_000790905.1 lactococcin 972 family bacteriocin -
- 1361676..1361713 + 38 - - Antitoxin
DXE41_RS07195 1361766..1361873 - 108 WP_000623369.1 putative holin-like toxin Toxin
DXE41_RS07200 1362143..1362745 - 603 WP_001033867.1 CPBP family intramembrane metalloprotease -
DXE41_RS07205 1362760..1362936 - 177 WP_000214898.1 YkvS family protein -
DXE41_RS07210 1363135..1364121 + 987 WP_000668814.1 lipoate--protein ligase -
DXE41_RS07215 1364202..1364420 - 219 WP_000876826.1 IDEAL domain-containing protein -
DXE41_RS07220 1364630..1365199 + 570 WP_000287265.1 competence protein ComK -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-35)


Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 3801.69 Da        Isoelectric Point: 10.8004

>T294304 WP_000623369.1 NZ_LT992475:c1361873-1361766 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Download         Length: 108 bp


Antitoxin


Download         Length: 38 bp

>AT294304 NZ_LT992475:1361676-1361713 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References