Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 192669..192948 Replicon chromosome
Accession NZ_LT992475
Organism Staphylococcus aureus isolate 20_LA_415

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DXE41_RS01070 Protein ID WP_001802298.1
Coordinates 192669..192773 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 192769..192948 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE41_RS01035 188568..189176 + 609 WP_000101714.1 TIR domain-containing protein -
DXE41_RS01040 189466..190248 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
DXE41_RS01045 190316..191173 + 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
DXE41_RS01050 191303..191395 - 93 WP_000220902.1 hypothetical protein -
DXE41_RS01055 191831..191989 - 159 WP_001792784.1 hypothetical protein -
DXE41_RS01070 192669..192773 + 105 WP_001802298.1 hypothetical protein Toxin
- 192769..192948 - 180 - - Antitoxin
DXE41_RS01075 193271..194362 - 1092 WP_000495673.1 hypothetical protein -
DXE41_RS01080 194628..195608 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
DXE41_RS01085 195610..195930 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DXE41_RS01090 196082..196747 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T294296 WP_001802298.1 NZ_LT992475:192669-192773 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 180 bp

>AT294296 NZ_LT992475:c192948-192769 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References