Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2823533..2823750 Replicon chromosome
Accession NZ_LT992474
Organism Staphylococcus aureus isolate 19_LA_388

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag DXE66_RS14570 Protein ID WP_114639807.1
Coordinates 2823646..2823750 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2823533..2823588 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE66_RS14550 2819672..2820337 - 666 WP_001024099.1 SDR family oxidoreductase -
DXE66_RS14555 2820489..2820809 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DXE66_RS14560 2820811..2821791 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
DXE66_RS14565 2822057..2823148 + 1092 WP_000495673.1 hypothetical protein -
- 2823533..2823588 + 56 - - Antitoxin
DXE66_RS14570 2823646..2823750 - 105 WP_114639807.1 hypothetical protein Toxin
DXE66_RS14585 2824430..2824588 + 159 WP_001792784.1 hypothetical protein -
DXE66_RS14590 2825024..2825116 + 93 WP_000220902.1 hypothetical protein -
DXE66_RS14595 2825246..2826103 - 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
DXE66_RS14600 2826171..2826953 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
DXE66_RS14605 2827243..2827851 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3872.75 Da        Isoelectric Point: 5.5724

>T294294 WP_114639807.1 NZ_LT992474:c2823750-2823646 [Staphylococcus aureus]
MLLLERTSMSDLEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT294294 NZ_LT992474:2823533-2823588 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References