Detailed information of TA system TA294285

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1655038..1655287
• Replicon: chromosome
• Accession: NZ_LT992474
• Organism: Staphylococcus aureus isolate 19_LA_388

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: DXE66_RS08445
• Protein ID: WP_000623369.1
• Coordinates: 1655038..1655145 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1655140..1655287 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DXE66_RS08420	1651712..1652281	-	570	WP_000287265.1	competence protein ComK	-
DXE66_RS08425	1652491..1652709	+	219	WP_000876826.1	IDEAL domain-containing protein	-
DXE66_RS08430	1652790..1653776	-	987	WP_000668814.1	lipoate--protein ligase	-
DXE66_RS08435	1653975..1654151	+	177	WP_000214898.1	YkvS family protein	-
DXE66_RS08440	1654166..1654768	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
DXE66_RS08445	1655038..1655145	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1655140..1655287	-	148	-	-	Antitoxin
DXE66_RS08450	1655780..1656064	+	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
DXE66_RS08455	1656108..1658072	+	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
DXE66_RS08460	1658075..1658395	+	321	WP_000668623.1	YxeA family protein	-
DXE66_RS08465	1658392..1659033	+	642	WP_000571192.1	ABC transporter ATP-binding protein	-
DXE66_RS08470	1659121..1659411	-	291	WP_001796515.1	hypothetical protein	-
DXE66_RS08475	1659501..1659689	+	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
DXE66_RS08480	1659778..1660134	-	357	WP_000766009.1	DoxX family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T294285 WP_000623369.1 NZ_LT992474:1655038-1655145 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 148 bp

>AT294285 NZ_LT992474:c1655287-1655140 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGTAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTGCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin