Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 273283..273467 Replicon chromosome
Accession NZ_LT992474
Organism Staphylococcus aureus isolate 19_LA_388

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DXE66_RS01500 Protein ID WP_000482647.1
Coordinates 273360..273467 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 273283..273343 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE66_RS01475 268737..268904 - 168 WP_001798790.1 hypothetical protein -
DXE66_RS01485 269135..270868 - 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
DXE66_RS01490 270893..272656 - 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
- 273283..273343 + 61 - - Antitoxin
DXE66_RS01500 273360..273467 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DXE66_RS01505 273601..273987 - 387 WP_000779355.1 flippase GtxA -
DXE66_RS01510 274254..275396 + 1143 WP_001176859.1 glycerate kinase -
DXE66_RS01515 275456..276115 + 660 WP_000831300.1 hypothetical protein -
DXE66_RS01520 276303..277514 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
DXE66_RS01525 277637..278110 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T294280 WP_000482647.1 NZ_LT992474:c273467-273360 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T294280 NZ_LT992474:c273467-273360 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT294280 NZ_LT992474:273283-273343 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References