Detailed information of TA system TA294264

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 848106..848303
• Replicon: chromosome
• Accession: NZ_LT992473
• Organism: Staphylococcus aureus isolate 14_5418

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: DXE48_RS04150
• Protein ID: WP_000623369.1
• Coordinates: 848196..848303 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	848106..848143 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DXE48_RS04115	843207..843563	+	357	WP_000766009.1	DoxX family protein	-
DXE48_RS04120	843652..843840	-	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
DXE48_RS04125	843930..844220	+	291	WP_001796515.1	hypothetical protein	-
DXE48_RS04130	844308..844949	-	642	WP_000571192.1	ABC transporter ATP-binding protein	-
DXE48_RS04135	844946..845266	-	321	WP_000668623.1	YxeA family protein	-
DXE48_RS04140	845269..847233	-	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
DXE48_RS04145	847277..847561	-	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
-	848106..848143	+	38	-	-	Antitoxin
DXE48_RS04150	848196..848303	-	108	WP_000623369.1	putative holin-like toxin	Toxin
DXE48_RS04155	848573..849175	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
DXE48_RS04160	849190..849366	-	177	WP_000214898.1	YkvS family protein	-
DXE48_RS04165	849565..850551	+	987	WP_000668814.1	lipoate--protein ligase	-
DXE48_RS04170	850632..850850	-	219	WP_000876826.1	IDEAL domain-containing protein	-
DXE48_RS04175	851060..851629	+	570	WP_000287265.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T294264 WP_000623369.1 NZ_LT992473:c848303-848196 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 38 bp

>AT294264 NZ_LT992473:848106-848143 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin