Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 330870..331087 Replicon chromosome
Accession NZ_LT992472
Organism Staphylococcus aureus isolate 10_5235

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DXE26_RS01880 Protein ID WP_001802298.1
Coordinates 330983..331087 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 330870..330925 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE26_RS01860 327009..327674 - 666 WP_001024099.1 SDR family oxidoreductase -
DXE26_RS01865 327826..328146 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DXE26_RS01870 328148..329128 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
DXE26_RS01875 329394..330485 + 1092 WP_000495673.1 hypothetical protein -
- 330870..330925 + 56 - - Antitoxin
DXE26_RS01880 330983..331087 - 105 WP_001802298.1 hypothetical protein Toxin
DXE26_RS01895 331767..331925 + 159 WP_001792784.1 hypothetical protein -
DXE26_RS01900 332361..332453 + 93 WP_000220902.1 hypothetical protein -
DXE26_RS01905 332583..333440 - 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
DXE26_RS01910 333508..334290 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
DXE26_RS01915 334580..335188 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T294256 WP_001802298.1 NZ_LT992472:c331087-330983 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT294256 NZ_LT992472:330870-330925 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References