294252

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2626675..2626859 Replicon chromosome
Accession NZ_LT992471
Organism Staphylococcus aureus isolate 17_LA_343

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DXE46_RS13760 Protein ID WP_000482647.1
Coordinates 2626752..2626859 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2626675..2626735 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE46_RS13735 2622129..2622296 - 168 WP_001798790.1 hypothetical protein -
DXE46_RS13745 2622527..2624260 - 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
DXE46_RS13750 2624285..2626048 - 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
- 2626675..2626735 + 61 - - Antitoxin
DXE46_RS13760 2626752..2626859 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DXE46_RS13765 2626993..2627379 - 387 WP_000779355.1 flippase GtxA -
DXE46_RS13770 2627646..2628788 + 1143 WP_001176859.1 glycerate kinase -
DXE46_RS13775 2628848..2629507 + 660 WP_000831300.1 hypothetical protein -
DXE46_RS13780 2629695..2630906 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
DXE46_RS13785 2631029..2631502 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T294252 WP_000482647.1 NZ_LT992471:c2626859-2626752 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT294252 NZ_LT992471:2626675-2626735 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References