Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2426384..2426663 Replicon chromosome
Accession NZ_LT992470
Organism Staphylococcus aureus isolate 13_LA_301

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DXE64_RS12345 Protein ID WP_001802298.1
Coordinates 2426384..2426488 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2426484..2426663 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE64_RS12310 2422283..2422891 + 609 WP_000101714.1 TIR domain-containing protein -
DXE64_RS12315 2423181..2423963 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
DXE64_RS12320 2424031..2424888 + 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
DXE64_RS12325 2425018..2425110 - 93 WP_000220902.1 hypothetical protein -
DXE64_RS12330 2425546..2425704 - 159 WP_001792784.1 hypothetical protein -
DXE64_RS12345 2426384..2426488 + 105 WP_001802298.1 hypothetical protein Toxin
- 2426484..2426663 - 180 - - Antitoxin
DXE64_RS12350 2426986..2428077 - 1092 WP_000495673.1 hypothetical protein -
DXE64_RS12355 2428343..2429323 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
DXE64_RS12360 2429325..2429645 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DXE64_RS12365 2429797..2430462 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T294229 WP_001802298.1 NZ_LT992470:2426384-2426488 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 180 bp

>AT294229 NZ_LT992470:c2426663-2426484 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References