294227

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2130658..2130842 Replicon chromosome
Accession NZ_LT992470
Organism Staphylococcus aureus isolate 13_LA_301

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DXE64_RS10730 Protein ID WP_000482647.1
Coordinates 2130658..2130765 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2130782..2130842 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE64_RS10705 2126015..2126488 + 474 WP_000456489.1 GyrI-like domain-containing protein -
DXE64_RS10710 2126611..2127822 - 1212 WP_001191974.1 multidrug effflux MFS transporter -
DXE64_RS10715 2128010..2128669 - 660 WP_000831300.1 hypothetical protein -
DXE64_RS10720 2128729..2129871 - 1143 WP_001176859.1 glycerate kinase -
DXE64_RS10725 2130138..2130524 + 387 WP_000779355.1 flippase GtxA -
DXE64_RS10730 2130658..2130765 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2130782..2130842 - 61 - - Antitoxin
DXE64_RS10740 2131469..2133232 + 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
DXE64_RS10745 2133257..2134990 + 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
DXE64_RS10755 2135221..2135388 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T294227 WP_000482647.1 NZ_LT992470:2130658-2130765 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT294227 NZ_LT992470:c2130842-2130782 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References