Detailed information of TA system TA294221

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 751803..752000
• Replicon: chromosome
• Accession: NZ_LT992470
• Organism: Staphylococcus aureus isolate 13_LA_301

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: DXE64_RS03810
• Protein ID: WP_000623369.1
• Coordinates: 751893..752000 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	751803..751840 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DXE64_RS03775	746904..747260	+	357	WP_000766009.1	DoxX family protein	-
DXE64_RS03780	747349..747537	-	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
DXE64_RS03785	747627..747917	+	291	WP_001796515.1	hypothetical protein	-
DXE64_RS03790	748005..748646	-	642	WP_000571192.1	ABC transporter ATP-binding protein	-
DXE64_RS03795	748643..748963	-	321	WP_000668623.1	YxeA family protein	-
DXE64_RS03800	748966..750930	-	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
DXE64_RS03805	750974..751258	-	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
-	751803..751840	+	38	-	-	Antitoxin
DXE64_RS03810	751893..752000	-	108	WP_000623369.1	putative holin-like toxin	Toxin
DXE64_RS03815	752270..752872	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
DXE64_RS03820	752887..753063	-	177	WP_000214898.1	YkvS family protein	-
DXE64_RS03825	753262..754248	+	987	WP_000668814.1	lipoate--protein ligase	-
DXE64_RS03830	754329..754547	-	219	WP_000876826.1	IDEAL domain-containing protein	-
DXE64_RS03835	754757..755326	+	570	WP_000287265.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T294221 WP_000623369.1 NZ_LT992470:c752000-751893 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 38 bp

>AT294221 NZ_LT992470:751803-751840 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin