294220

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2607857..2608041 Replicon chromosome
Accession NZ_LT992469
Organism Staphylococcus aureus isolate 15_LA_305

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DXE36_RS13380 Protein ID WP_000482647.1
Coordinates 2607857..2607964 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2607981..2608041 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE36_RS13355 2603214..2603687 + 474 WP_000456489.1 GyrI-like domain-containing protein -
DXE36_RS13360 2603810..2605021 - 1212 WP_001191974.1 multidrug effflux MFS transporter -
DXE36_RS13365 2605209..2605868 - 660 WP_000831300.1 hypothetical protein -
DXE36_RS13370 2605928..2607070 - 1143 WP_001176859.1 glycerate kinase -
DXE36_RS13375 2607337..2607723 + 387 WP_000779355.1 flippase GtxA -
DXE36_RS13380 2607857..2607964 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2607981..2608041 - 61 - - Antitoxin
DXE36_RS13390 2608668..2610431 + 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
DXE36_RS13395 2610456..2612189 + 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
DXE36_RS13405 2612420..2612587 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T294220 WP_000482647.1 NZ_LT992469:2607857-2607964 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT294220 NZ_LT992469:c2608041-2607981 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References