Detailed information of TA system TA294217

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1274182..1274379
• Replicon: chromosome
• Accession: NZ_LT992469
• Organism: Staphylococcus aureus isolate 15_LA_305

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: DXE36_RS06780
• Protein ID: WP_000623369.1
• Coordinates: 1274272..1274379 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	1274182..1274219 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DXE36_RS06745	1269283..1269639	+	357	WP_000766009.1	DoxX family protein	-
DXE36_RS06750	1269728..1269916	-	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
DXE36_RS06755	1270006..1270296	+	291	WP_001796515.1	hypothetical protein	-
DXE36_RS06760	1270384..1271025	-	642	WP_000571192.1	ABC transporter ATP-binding protein	-
DXE36_RS06765	1271022..1271342	-	321	WP_000668623.1	YxeA family protein	-
DXE36_RS06770	1271345..1273309	-	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
DXE36_RS06775	1273353..1273637	-	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
-	1274182..1274219	+	38	-	-	Antitoxin
DXE36_RS06780	1274272..1274379	-	108	WP_000623369.1	putative holin-like toxin	Toxin
DXE36_RS06785	1274649..1275251	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
DXE36_RS06790	1275266..1275442	-	177	WP_000214898.1	YkvS family protein	-
DXE36_RS06795	1275641..1276627	+	987	WP_000668814.1	lipoate--protein ligase	-
DXE36_RS06800	1276708..1276926	-	219	WP_000876826.1	IDEAL domain-containing protein	-
DXE36_RS06805	1277136..1277705	+	570	WP_000287260.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T294217 WP_000623369.1 NZ_LT992469:c1274379-1274272 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 38 bp

>AT294217 NZ_LT992469:1274182-1274219 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin