294205

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-SprA2AS/-
Location 75195..75458 Replicon chromosome
Accession NZ_LT992469
Organism Staphylococcus aureus isolate 15_LA_305

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DXE36_RS00400 Protein ID WP_001802298.1
Coordinates 75195..75299 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 75294..75458 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE36_RS00365 71094..71702 + 609 WP_000101714.1 TIR domain-containing protein -
DXE36_RS00370 71992..72774 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
DXE36_RS00375 72842..73699 + 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
DXE36_RS00380 73829..73921 - 93 WP_000220902.1 hypothetical protein -
DXE36_RS00385 74357..74515 - 159 WP_001792784.1 hypothetical protein -
DXE36_RS00400 75195..75299 + 105 WP_001802298.1 hypothetical protein Toxin
- 75294..75458 - 165 - - Antitoxin
DXE36_RS00405 75797..76888 - 1092 WP_000495673.1 hypothetical protein -
DXE36_RS00410 77154..78134 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
DXE36_RS00415 78136..78456 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DXE36_RS00420 78608..79273 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T294205 WP_001802298.1 NZ_LT992469:75195-75299 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT294205 NZ_LT992469:c75458-75294 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References