Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1005560..1005744 Replicon chromosome
Accession NZ_LT992468
Organism Staphylococcus aureus isolate 12_LA_293

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DXE47_RS05770 Protein ID WP_000482647.1
Coordinates 1005637..1005744 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1005560..1005620 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE47_RS05745 1001014..1001181 - 168 WP_001798790.1 hypothetical protein -
DXE47_RS05755 1001412..1003145 - 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
DXE47_RS05760 1003170..1004933 - 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
- 1005560..1005620 + 61 - - Antitoxin
DXE47_RS05770 1005637..1005744 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DXE47_RS05775 1005878..1006264 - 387 WP_000779355.1 flippase GtxA -
DXE47_RS05780 1006531..1007673 + 1143 WP_001176859.1 glycerate kinase -
DXE47_RS05785 1007733..1008392 + 660 WP_000831300.1 hypothetical protein -
DXE47_RS05790 1008580..1009791 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
DXE47_RS05795 1009914..1010387 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T294200 WP_000482647.1 NZ_LT992468:c1005744-1005637 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT294200 NZ_LT992468:1005560-1005620 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References