Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1066777..1066961 Replicon chromosome
Accession NZ_LT992467
Organism Staphylococcus aureus isolate 16_LA_309

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DXE59_RS05730 Protein ID WP_000482647.1
Coordinates 1066854..1066961 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1066777..1066837 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE59_RS05705 1062231..1062398 - 168 WP_001798790.1 hypothetical protein -
DXE59_RS05715 1062629..1064362 - 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
DXE59_RS05720 1064387..1066150 - 1764 WP_114636079.1 ABC transporter ATP-binding protein/permease -
- 1066777..1066837 + 61 - - Antitoxin
DXE59_RS05730 1066854..1066961 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DXE59_RS05735 1067095..1067481 - 387 WP_000779355.1 flippase GtxA -
DXE59_RS05740 1067748..1068890 + 1143 WP_001176859.1 glycerate kinase -
DXE59_RS05745 1068950..1069609 + 660 WP_000831300.1 hypothetical protein -
DXE59_RS05750 1069797..1071008 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
DXE59_RS05755 1071131..1071604 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T294187 WP_000482647.1 NZ_LT992467:c1066961-1066854 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT294187 NZ_LT992467:1066777-1066837 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References